Clinical Trials MCP Server & Skill

AI Skill
SKILL.md

Domain knowledge for Clinical Trials — workflow patterns, data models, and gotchas for your AI agent.

Clinical Trials

580,000+ registered clinical studies from ClinicalTrials.gov, updated daily.

Workflows

Patient looking for a trial: Search condition + RECRUITING + location → review eligibility from results → get detail for inclusion/exclusion criteria and contacts.

Drug pipeline analysis: Search intervention (drug name) across all statuses → count by phase → detail on Phase 3 trials → search sponsor for full portfolio.

Competitive landscape: Search condition + PHASE3 → group by sponsor → note enrollment sizes → search by drug class.

Market sizing: Use count tool with condition + status + phase combinations. Sort by StartDate:desc to track acceleration.

Key Concepts

Status lifecycle: NOT_YET_RECRUITING → RECRUITING → ACTIVE_NOT_RECRUITING → COMPLETED (or TERMINATED/WITHDRAWN)
Phases: EARLY_PHASE1 → PHASE1 → PHASE2 → PHASE3 → PHASE4. Phase 3 is pivotal for FDA approval.
Sponsor class: INDUSTRY (pharma), NIH, OTHER_GOV, NETWORK, OTHER (academic)
Search strategy: condition is strongest. Use generic drug names for intervention. Combine condition + phase + status for precision.
Sort by LastUpdatePostDate:desc for recent activity, EnrollmentCount:desc for largest studies.

Gotchas

Status/phase values are UPPERCASE and case-sensitive.
Search returns summaries; use detail tool with NCT ID for full eligibility, locations, contacts.
has_results=true means outcome data posted (~30% of completed trials).
Pagination is cursor-based (next_page_token), not offset-based.

Tools in this Server (3)

Clinical Trials Count

Count clinical trials matching search criteria. Returns only the total count — faster than search when you just need numbers. Filter by condition, int...

Clinical Trials Get Study

Get full details for a clinical trial by its NCT ID. Returns the complete study record including eligibility criteria, detailed description, study des...

Clinical Trials Search

Search ClinicalTrials.gov for clinical studies. Filter by condition (disease), intervention (drug/device), sponsor, phase, recruitment status, and loc...

Frequently Asked Questions

What is the Clinical Trials MCP server?

Search and analyze 580,000+ clinical trials from ClinicalTrials.gov. Find studies by condition, drug, sponsor, phase, recruitment status, and location. Get full study details including eligibility criteria, outcomes, design, locations, and contacts. Count trials for market sizing. It provides 3 tools that AI agents can use through the Model Context Protocol (MCP).

How do I connect Clinical Trials to my AI agent?

Add the MCPBundles server URL to your MCP client configuration (Claude Desktop, Cursor, VS Code, etc.). The URL format is: https://mcp.mcpbundles.com/bundle/clinical-trials. Authentication is handled automatically.

How many tools does Clinical Trials provide?

Clinical Trials provides 3 tools that can be called by AI agents, along with a SKILL.md that gives your AI agent domain knowledge about when and how to use them.

What authentication does Clinical Trials require?

Clinical Trials uses open data APIs — no authentication required.